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23 results for Lymph
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A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses, J. Appl, Toxicology, 19, 261-266. [EU] Toxicology, 19, 261-266.

Art der Probe: L = Lymphknoten (lymph nodes), S = Abstrich (swab), MJ = Fleischsaft (meat juice). [EU] Tipo de muestra: L = ganglios linfáticos, E = muestras tomadas con la esponja, JC = jugo de carne.

Assessment of the skin sensitisation potential of topical medicaments, using the local lymph node assay: An interlaboratory exercise, Journal of Toxicology and Environmental Health, 53, 563-79. [EU] Journal of Toxicology and Environmental Health, 53, 563-79.

Baskelter, D.A., Gerberick, G.F., Kimber, I., and Loveless, S.E (1996). The local lymph node assay- A viable alternative to currently accepted skin sensitisation tests. [EU] Basketter, D.A., Gerberick, G.F., Kimber, I. and Loveless, S.E (1996). The local lymph node assay- A viable altemative to currently skin sensitisation tests.

Basketter, D.A, Blaikie, L, Derman, R.J., Kimber, I., Ryan, C.A., Gerberick, G.F., Harvey, P., Evans, P., White, IR., and Rycroft, R.T.G. (2000). Use of local lymph node assay for the estimation of relative contact allergenic potency. [EU] Basketter DA, Blaikie L, Derman RJ, Kimber I, Ryan CA, Gerberick GF, Harvey P, Evans P, White IR and Rycroft RTG (2000). Use of local lymph node assay for the estimation of relative contact allergenic potency.

Chamberlain, M., and Basketter, D.A. (1996). The local lymph node assay: status of validation. [EU] Chamberlain, M. and Basketter, D.A. (1996). The local lymph node assay: status of validation.

Dearman, R.J., Hilton, J., Evans, P., Harvey, P., Basketter, D.A., and Kimber, I. (1998). Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde. [EU] Dearman, R.J., Hilton, J., Evans, P., Harvey, P., Basketter, D.A. and Kimber, I. (1998). Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde.

Der lokale Lymphknoten test (local lymph node assay = LLNA) ist hinreichend validiert worden und kann daher als eigenständige Methode akzeptiert werden (1) (2) (3). [EU] El ensayo con ganglios linfáticos locales (Local Lymph Node Assay, LLNA) ha sido suficientemente validado y aceptado para justificar su adopción como nuevo método (1) (2) (3).

Die bei diesen Untersuchungen genutzten Verfahren sollten den OECD-Leitlinien 404 (Acute Dermal Irritation/Corrosion), 405 (Acute Eye Irritation/Corrosion), 406 (Skin Sensitisation) und 429 (Skin Sensitisation: Local Lymph Node Assay) entsprechen. [EU] Los protocolos de estos estudios deberán estar en consonancia con las Directrices de la OCDE nos 404 (efecto irritante o corrosivo en la piel), 405 (efecto irritante o corrosivo en los ojos), 406 (sensibilización cutánea) y 429 (sensibilización cutánea: ensayo de ganglios linfáticos locales).

Die ursprüngliche Prüfmethode (B.42) zur Bestimmung der Hautsensibilisierung bei der Maus, der Lokale Lymphknotentest (Local Lymph Node Assay bzw. LLNA; OECD-Prüfrichtlinie 429) wurde inzwischen überarbeitet (1, und Kapitel B.42 in diesem Anhang). [EU] Se ha revisado el primer método de ensayo (ME) para la determinación de la sensibilización cutánea con ratones, la prueba con ganglios linfáticos locales (LLNA, de su nombre en inglés, que corresponde a la TG 429 de la OCDE, capítulo B.42 del presente anexo) (1).

Die ursprüngliche Prüfmethode (B.42) zur Bestimmung der Hautsensibilisierung bei der Maus, der Lokale Lymphknotentest (Local Lymph Node Assay bzw. LLNA; OECD-Prüfrichtlinie 429) wurde inzwischen überarbeitet (1). Verschiedene Veröffentlichungen (2) (3) (4) (5) (6) (7) (8) (9) gehen genauer auf die Validierung des LLNA und auf die mit ihm verbundenen wissenschaftlichen Arbeiten ein. [EU] Se ha revisado el primer método de ensayo (ME) para la determinación de la sensibilización cutánea con ratones, la prueba con ganglios linfáticos locales (LLNA, de su nombre en inglés, que corresponde a la TG 429 de la OCDE, capítulo B.42 del presente anexo) (1). Se han publicado los datos de la validación del LLNA, así como una revisión de los trabajos asociados (2) (3) (4) (5) (6) (7) (8) (9).

Die ursprüngliche Prüfmethode zur Bestimmung der Hautsensibilisierung bei der Maus, der Lokale Lymphknotentest (Local Lymph Node Assay bzw. LLNA; OECD-Prüfrichtlinie 429; Kapitel B.42 dieses Anhangs), wurde bereits vor einiger Zeit zugelassen (1). [EU] Ya se ha adoptado el método de ensayo (ME) original para la determinación de la sensibilización cutánea con ratones, la prueba con ganglios linfáticos locales (LLNA, de su nombre en inglés, que corresponde a la TG 429 de la OCDE, capítulo B.42 del presente anexo) (1).

ESAC (2007), Statement on the Reduced Local Lymph Node Assay (rLLNA), European Commission Directorate General, Joint Research Centre, Institute for Health and Consumer Protection, European Centre for the Validation of Alternative Methods, April 2007. [EU] Comité Científico Consultivo del CEVMA (2007), Statement on the Reduced Local Lymph Node Assay (rLLNA), Comisión Europea, Dirección General Centro Común de Investigación, Instituto de Sanidad y Protección de los Consumidores, Centro Europeo para la Validación de Métodos Alternativos, april 2007.

ICCVAM (1999), The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds, The Results of an Independent Peer Review Evaluation Coordinated by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), NIH Publication No. 99-4494, Research Triangle Park, NC: National Institute of Environmental Health Sciences. [EU] ICCVAM (1999), The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds, The Results of an Independent Peer Review Evaluation Coordinated by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), NIH Publication No. 99-4494, Research Triangle Park, NC: National Institute of Environmental Health Sciences.

, ICCVAM evaluation of the murine local lymph node assay: I. The ICCVAM review process.Reg. [EU] , ICCVAM evaluation of the murine local lymph node assay: I. The ICCVAM review process.Reg.

Idehara, K., Yamagishi, G., Yamashita, K. and Ito, M. (2008), Characterization and evaluation of a modified local lymph node assay using ATP content as a non-radio isotopic endpoint.J. [EU] Idehara, K., Yamagishi, G., Yamashita, K. and Ito, M. (2008), Characterization and evaluation of a modified local lymph node assay using ATP content as a non-radio isotopic endpoint.J.

Kimber, J., Hilton, X, Dearman, R.J., Gerberick, G.F., Ryan, CA., Basketter, D.A., Lea, L., House, R.V., Ladies, G.S., Loveless, S.E., Hastings, K.L. (1998). [EU] Kimber, I., Hilton, J., Dearman, R.J., Gerberick, G.F., Ryan, C.A., Basketter, D.A., Lea, L., House, R.V., Ladies, G.S., Loveless, S.E., Hastings, K.L. (1998). Assessment of the skin sensitisation potential of topical medicaments using the local lymph node assay: An interlaboratory exercise.

Kimber, L, and Basketter, D.A. (1992). The murine local lymph node assay; collaborative studies and new directions:-A commentary. [EU] Kimber, I. and Basketter, D.A. (1992). The murine local lymph node assay; collaborative studies and new directions: A commentary.

National Institute of Environmental Health Sciences (1999). The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds: The Results of an Independent Peer Review Evaluation Coordinated by the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the National Toxicology Program Center for the Evaluation of Alternative Toxicological Methods (NICETAM). [EU] National Institute of Environmental Health Sciences (1999). The. Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds: The Results of an Independent Peer Review Evaluation Coordinated by the Interagency Coordinating Committee on the Validation of Altemative Methods (ICCVAM) and the National Toxicology Program Center for the Evaluation of Altemative Toxicological Methods (NICETAM).

Nonradioactive local lymph node assay: modified by Daicel Chemical Industries, Ltd., based on ATP content test method protocol (LLNA: DA). [EU] Nonradioactive local lymph node assay: modified by Daicel Chemical Industries, Ltd., based on ATP content test method protocol (LLNA: DA).

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